1 | /** |
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2 | * AssayService Service |
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3 | * |
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4 | * @author s.h.sikkema@gmail.com |
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5 | * @since 20101216 |
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6 | * @package dbnp.studycapturing |
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7 | * |
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8 | * Revision information: |
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9 | * $Rev: 1803 $ |
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10 | * $Author: s.h.sikkema@gmail.com $ |
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11 | * $Date: 2011-05-04 07:53:40 +0000 (wo, 04 mei 2011) $ |
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12 | */ |
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13 | package dbnp.studycapturing |
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14 | |
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15 | import org.apache.poi.ss.usermodel.* |
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16 | import org.apache.poi.xssf.usermodel.XSSFWorkbook |
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17 | import org.apache.poi.hssf.usermodel.HSSFWorkbook |
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18 | import org.codehaus.groovy.grails.web.json.JSONObject |
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19 | import org.dbnp.gdt.RelTime |
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20 | import org.dbnp.gdt.TemplateFieldType; |
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21 | |
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22 | class AssayService { |
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23 | |
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24 | boolean transactional = false |
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25 | def authenticationService |
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26 | def moduleCommunicationService |
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27 | |
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28 | /** |
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29 | * Collects the assay field names per category in a map as well as the |
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30 | * module's measurements. |
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31 | * |
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32 | * @param assay the assay for which to collect the fields |
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33 | * @return a map of categories as keys and field names or measurements as |
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34 | * values |
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35 | */ |
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36 | def collectAssayTemplateFields(assay) throws Exception { |
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37 | |
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38 | def getUsedTemplateFields = { templateEntities -> |
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39 | |
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40 | // gather all unique and non null template fields that haves values |
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41 | templateEntities*.giveFields().flatten().unique().findAll{ field -> |
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42 | |
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43 | field && templateEntities.any { it?.fieldExists(field.name) && it.getFieldValue(field.name) != null } |
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44 | |
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45 | }.collect{[name: it.name, comment: it.comment, displayName: it.name + (it.unit ? " ($it.unit)" : '')]} |
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46 | } |
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47 | |
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48 | def samples = assay.samples |
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49 | [ 'Subject Data' : getUsedTemplateFields( samples*."parentSubject".unique() ), |
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50 | 'Sampling Event Data' : getUsedTemplateFields( samples*."parentEvent".unique() ), |
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51 | 'Sample Data' : getUsedTemplateFields( samples ), |
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52 | 'Event Group' : [[name: 'name', comment: 'Name of Event Group', displayName: 'name']], |
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53 | |
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54 | // If module is not reachable, only the field 'module error' is returned, and is filled later on. |
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55 | 'Module Measurement Data': moduleCommunicationService.isModuleReachable(assay.module.url) ? requestModuleMeasurementNames(assay) : [ [ name: "Module error" ] ] |
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56 | ] |
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57 | |
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58 | } |
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59 | |
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60 | /** |
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61 | * Gathers all assay related data, including measurements from the module, |
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62 | * into 1 hash map containing: Subject Data, Sampling Event Data, Sample |
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63 | * Data, and module specific measurement data. |
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64 | * Data from each of the 4 hash map entries are themselves hash maps |
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65 | * representing a descriptive header (field name) as key and the data as |
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66 | * value. |
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67 | * |
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68 | * @param assay the assay to collect data for |
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69 | * @param fieldMap map with categories as keys and fields as values |
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70 | * @param measurementTokens selection of measurementTokens |
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71 | * @return The assay data structure as described above. |
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72 | */ |
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73 | def collectAssayData(assay, fieldMap, measurementTokens) throws Exception { |
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74 | |
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75 | def collectFieldValuesForTemplateEntities = { headerFields, templateEntities -> |
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76 | |
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77 | // return a hash map with for each field name all values from the |
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78 | // template entity list |
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79 | headerFields.inject([:]) { map, headerField -> |
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80 | |
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81 | map + [(headerField.displayName): templateEntities.collect { |
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82 | |
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83 | // default to an empty string |
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84 | def val = '' |
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85 | |
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86 | def field |
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87 | try { |
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88 | |
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89 | val = it.getFieldValue(headerField.name) |
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90 | |
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91 | // Convert RelTime fields to human readable strings |
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92 | field = it.getField(headerField.name) |
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93 | if (field.type == TemplateFieldType.RELTIME) |
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94 | val = new RelTime( val as long ) |
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95 | |
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96 | } catch (NoSuchFieldException e) { /* pass */ } |
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97 | |
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98 | val.toString()}] |
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99 | } |
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100 | } |
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101 | |
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102 | def getFieldValues = { templateEntities, headerFields, propertyName = '' -> |
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103 | |
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104 | def returnValue |
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105 | |
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106 | // if no property name is given, simply collect the fields and |
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107 | // values of the template entities themselves |
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108 | if (propertyName == '') { |
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109 | |
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110 | returnValue = collectFieldValuesForTemplateEntities(headerFields, templateEntities) |
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111 | |
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112 | } else { |
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113 | |
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114 | // if a property name is given, we'll have to do a bit more work |
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115 | // to ensure efficiency. The reason for this is that for a list |
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116 | // of template entities, the properties referred to by |
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117 | // propertyName can include duplicates. For example, for 10 |
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118 | // samples, there may be less than 10 parent subjects. Maybe |
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119 | // there's only 1 parent subject. We don't want to collect field |
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120 | // values for this single subject 10 times ... |
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121 | def fieldValues |
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122 | |
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123 | // we'll get the unique list of properties to make sure we're |
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124 | // not getting the field values for identical template entity |
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125 | // properties more then once. |
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126 | def uniqueProperties = templateEntities*."$propertyName".unique() |
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127 | |
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128 | fieldValues = collectFieldValuesForTemplateEntities(headerFields, uniqueProperties) |
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129 | |
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130 | // prepare a lookup hashMap to be able to map an entities' |
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131 | // property (e.g. a sample's parent subject) to an index value |
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132 | // from the field values list |
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133 | int i = 0 |
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134 | def propertyToFieldValueIndexMap = uniqueProperties.inject([:]) { map, item -> map + [(item):i++]} |
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135 | |
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136 | // prepare the return value so that it has an entry for field |
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137 | // name. This will be the column name (second header line). |
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138 | returnValue = headerFields*.displayName.inject([:]) { map, item -> map + [(item):[]] } |
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139 | |
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140 | // finally, fill map the unique field values to the (possibly |
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141 | // not unique) template entity properties. In our example with |
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142 | // 1 unique parent subject, this means copying that subject's |
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143 | // field values to all 10 samples. |
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144 | templateEntities.each{ te -> |
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145 | |
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146 | headerFields*.displayName.each{ |
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147 | |
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148 | returnValue[it] << fieldValues[it][propertyToFieldValueIndexMap[te[propertyName]]] |
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149 | |
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150 | } |
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151 | |
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152 | } |
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153 | |
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154 | } |
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155 | |
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156 | returnValue |
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157 | |
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158 | } |
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159 | |
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160 | // Find samples and sort by name |
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161 | def samples = assay.samples.toList().sort { it.name } |
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162 | |
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163 | def eventFieldMap = [:] |
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164 | |
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165 | // check whether event group data was requested |
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166 | if (fieldMap['Event Group']) { |
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167 | |
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168 | def names = samples*.parentEventGroup*.name.flatten() |
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169 | |
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170 | // only set name field when there's actual data |
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171 | if (!names.every {!it}) eventFieldMap['name'] = names |
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172 | |
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173 | } |
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174 | |
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175 | [ 'Subject Data' : getFieldValues(samples, fieldMap['Subject Data'], 'parentSubject'), |
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176 | 'Sampling Event Data' : getFieldValues(samples, fieldMap['Sampling Event Data'], 'parentEvent'), |
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177 | 'Sample Data' : getFieldValues(samples, fieldMap['Sample Data']), |
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178 | 'Event Group' : eventFieldMap, |
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179 | |
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180 | // If module is not reachable, only the message 'module not reachable' is given for each sample |
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181 | 'Module Measurement Data': moduleCommunicationService.isModuleReachable(assay.module.url) ? |
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182 | ( measurementTokens ? requestModuleMeasurements(assay, measurementTokens, samples) : [:] ) : |
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183 | [ "Module error": [ "Module not reachable" ] * samples.size() ] |
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184 | ] |
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185 | } |
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186 | |
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187 | /** |
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188 | * Prepend data from study to the data structure |
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189 | * @param assayData Column wise data structure of samples |
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190 | * @param assay Assay object the data should be selected from |
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191 | * @param numValues Number of values for this assay |
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192 | * @return Extended column wise data structure |
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193 | */ |
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194 | def prependStudyData( inputData, Assay assay, numValues ) { |
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195 | if( !assay ) |
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196 | return inputData; |
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197 | |
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198 | // Retrieve study data |
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199 | def studyData =[:] |
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200 | assay.parent?.giveFields().each { |
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201 | def value = assay.parent.getFieldValue( it.name ) |
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202 | if( value ) |
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203 | studyData[ it.name ] = [value] * numValues |
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204 | } |
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205 | |
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206 | return [ |
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207 | 'Study Data': studyData |
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208 | ] + inputData |
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209 | } |
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210 | |
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211 | /** |
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212 | * Prepend data from assay to the data structure |
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213 | * @param assayData Column wise data structure of samples |
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214 | * @param assay Assay object the data should be selected from |
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215 | * @param numValues Number of values for this assay |
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216 | * @return Extended column wise data structure |
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217 | */ |
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218 | def prependAssayData( inputData, Assay assay, numValues ) { |
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219 | if( !assay ) |
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220 | return inputData; |
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221 | |
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222 | // Retrieve assay data |
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223 | def assayData = [:] |
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224 | assay.giveFields().each { |
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225 | def value = assay.getFieldValue( it.name ) |
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226 | if( value ) |
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227 | assayData[ it.name ] = [value] * numValues |
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228 | } |
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229 | |
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230 | return [ |
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231 | 'Assay Data': assayData |
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232 | ] + inputData |
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233 | } |
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234 | |
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235 | /** |
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236 | * Retrieves measurement names from the module through a rest call |
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237 | * |
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238 | * @param consumer the url of the module |
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239 | * @param path path of the rest call to the module |
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240 | * @return |
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241 | */ |
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242 | def requestModuleMeasurementNames(assay) { |
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243 | |
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244 | def moduleUrl = assay.module.url |
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245 | |
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246 | def path = moduleUrl + "/rest/getMeasurements/query?assayToken=$assay.assayUUID" |
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247 | |
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248 | def jsonArray = moduleCommunicationService.callModuleRestMethodJSON(moduleUrl, path) |
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249 | |
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250 | jsonArray.collect { |
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251 | if( it == JSONObject.NULL ) |
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252 | return "" |
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253 | else |
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254 | return it.toString() |
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255 | } |
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256 | |
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257 | } |
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258 | |
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259 | /** |
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260 | * Retrieves module measurement data through a rest call to the module |
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261 | * |
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262 | * @param assay Assay for which the module measurements should be retrieved |
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263 | * @param measurementTokens List with the names of the fields to be retrieved. Format: [ 'measurementName1', 'measurementName2' ] |
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264 | * @param samples Samples for which the module |
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265 | * @return |
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266 | */ |
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267 | def requestModuleMeasurements(assay, inputMeasurementTokens, samples) { |
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268 | |
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269 | def moduleUrl = assay.module.url |
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270 | |
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271 | def tokenString = '' |
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272 | |
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273 | inputMeasurementTokens.each{ |
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274 | tokenString+="&measurementToken=${it.encodeAsURL()}" |
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275 | } |
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276 | |
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277 | def path = moduleUrl + "/rest/getMeasurementData/query?assayToken=$assay.assayUUID" + tokenString |
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278 | |
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279 | def (sampleTokens, measurementTokens, moduleData) = moduleCommunicationService.callModuleRestMethodJSON(moduleUrl, path) |
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280 | |
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281 | if (!sampleTokens?.size()) return [] |
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282 | |
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283 | // Convert the three different maps into a map like: |
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284 | // |
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285 | // [ "measurement 1": [ value1, value2, value3 ], |
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286 | // "measurement 2": [ value4, value5, value6 ] ] |
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287 | // |
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288 | // The returned values should be in the same order as the given samples-list |
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289 | def map = [:] |
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290 | def numSampleTokens = sampleTokens.size(); |
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291 | |
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292 | measurementTokens.eachWithIndex { measurementToken, measurementIndex -> |
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293 | def measurements = []; |
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294 | samples.each { sample -> |
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295 | |
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296 | // Do measurements for this sample exist? If not, a null value is returned |
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297 | // for this sample. Otherwise, the measurement is looked up in the list with |
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298 | // measurements, based on the sample token |
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299 | if( sampleTokens.collect{ it.toString() }.contains( sample.giveUUID() ) ) { |
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300 | def tokenIndex = sampleTokens.indexOf( sample.giveUUID() ); |
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301 | def valueIndex = measurementIndex * numSampleTokens + tokenIndex; |
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302 | |
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303 | // If the module data is in the wrong format, show an error in the log file |
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304 | // and return a null value for this measurement. |
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305 | if( valueIndex >= moduleData.size() ) { |
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306 | log.error "Module measurements given by module " + assay.module.name + " are not in the right format: " + measurementTokens?.size() + " measurements, " + sampleTokens?.size() + " samples, " + moduleData?.size() + " values" |
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307 | measurements << null |
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308 | } else { |
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309 | measurements << ( moduleData[ valueIndex ] == JSONObject.NULL ? "" : moduleData[ valueIndex ].toString() ); |
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310 | } |
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311 | } else { |
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312 | measurements << null |
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313 | } |
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314 | } |
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315 | map[ measurementToken.toString() ] = measurements |
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316 | } |
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317 | |
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318 | return map; |
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319 | } |
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320 | |
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321 | /** |
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322 | * Merges the data from multiple studies into a structure that can be exported to an excel file. The format for each assay is |
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323 | * |
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324 | * [Category1: |
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325 | * [Column1: [1,2,3], Column2: [4,5,6]], |
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326 | * Category2: |
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327 | * [Column3: [7,8,9], Column4: [10,11,12], Column5: [13,14,15]]] |
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328 | * |
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329 | * Where the category describes the category of data that is presented (e.g. subject, sample etc.) and the column names describe |
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330 | * the fields that are present. Each entry in the lists shows the value for that column for an entity. In this case, 3 entities are described. |
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331 | * Each field should give values for all entities, so the length of all value-lists should be the same. |
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332 | * |
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333 | * Example: If the following input is given (2 assays) |
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334 | * |
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335 | * [ |
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336 | * [Category1: |
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337 | * [Column1: [1,2,3], Column2: [4,5,6]], |
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338 | * Category2: |
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339 | * [Column3: [7,8,9], Column4: [10,11,12], Column5: [13,14,15]]], |
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340 | * [Category1: |
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341 | * [Column1: [16,17], Column6: [18,19]], |
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342 | * Category3: |
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343 | * [Column3: [20,21], Column8: [22,23]]] |
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344 | * ] |
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345 | * |
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346 | * the output will be (5 entries for each column, empty values for fields that don't exist in some assays) |
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347 | * |
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348 | * [ |
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349 | * [Category1: |
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350 | * [Column1: [1,2,3,16,17], Column2: [4,5,6,,], Column6: [,,,18,19]], |
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351 | * Category2: |
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352 | * [Column3: [7,8,9,,], Column4: [10,11,12,,], Column5: [13,14,15,,]], |
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353 | * Category3: |
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354 | * [Column3: [,,,20,21], Column8: [,,,22,23]] |
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355 | * ] |
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356 | * |
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357 | * |
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358 | * @param columnWiseAssayData List with each entry being the column wise data of an assay. The format for each |
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359 | * entry is described above |
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360 | * @return Hashmap Combined assay data, in the same structure as each input entry. Empty values are given as an empty string. |
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361 | * So for input entries |
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362 | */ |
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363 | def mergeColumnWiseDataOfMultipleStudies(def columnWiseAssayData) { |
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364 | // Compute the number of values that is expected for each assay. This number is |
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365 | // used later on to determine the number of empty fields to add if a field is not present in this |
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366 | // assay |
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367 | def numValues = columnWiseAssayData.collect { assay -> |
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368 | for( cat in assay ) { |
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369 | if( cat ) { |
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370 | for( field in cat.value ) { |
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371 | if( field?.value?.size() > 0 ) { |
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372 | return field.value.size(); |
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373 | } |
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374 | } |
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375 | } |
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376 | } |
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377 | |
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378 | return 0; |
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379 | } |
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380 | |
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381 | // Merge categories from all assays. Create a list for all categories |
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382 | def categories = columnWiseAssayData*.keySet().toList().flatten().unique(); |
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383 | def mergedColumnWiseData = [:] |
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384 | categories.each { category -> |
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385 | // Only work with this category for all assays |
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386 | def categoryData = columnWiseAssayData*.getAt( category ); |
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387 | |
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388 | // Find the different fields in all assays |
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389 | def categoryFields = categoryData.findAll{ it }*.keySet().toList().flatten().unique(); |
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390 | |
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391 | // Find data for all assays for these fields. If the fields do not exist, return an empty string |
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392 | def categoryValues = [:] |
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393 | categoryFields.each { field -> |
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394 | categoryValues[ field ] = []; |
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395 | |
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396 | // Loop through all assays |
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397 | categoryData.eachWithIndex { assayValues, idx -> |
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398 | if( assayValues && assayValues.containsKey( field ) ) { |
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399 | // Append the values if they exist |
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400 | categoryValues[ field ] += assayValues[ field ]; |
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401 | } else { |
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402 | // Append empty string for each entity if the field doesn't exist |
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403 | categoryValues[ field ] += [""] * numValues[ idx ] |
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404 | } |
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405 | } |
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406 | } |
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407 | |
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408 | mergedColumnWiseData[ category ] = categoryValues |
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409 | } |
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410 | |
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411 | return mergedColumnWiseData; |
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412 | } |
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413 | |
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414 | /** |
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415 | * Converts column |
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416 | * @param columnData multidimensional map containing column data. |
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417 | * On the top level, the data must be grouped by category. Each key is the |
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418 | * category title and the values are maps representing the columns. Each |
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419 | * column also has a title (its key) and a list of values. Columns must be |
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420 | * equally sized. |
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421 | * |
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422 | * For example, consider the following map: |
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423 | * [Category1: |
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424 | * [Column1: [1,2,3], Column2: [4,5,6]], |
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425 | * Category2: |
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426 | * [Column3: [7,8,9], Column4: [10,11,12], Column5: [13,14,15]]] |
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427 | * |
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428 | * which will be written as: |
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429 | * |
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430 | * | Category1 | | Category2 | | | |
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431 | * | Column1 | Column2 | Column3 | Column4 | Column5 | |
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432 | * | 1 | 4 | 7 | 10 | 13 | |
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433 | * | 2 | 5 | 8 | 11 | 14 | |
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434 | * | 3 | 6 | 9 | 12 | 15 | |
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435 | * |
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436 | * @return row wise data |
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437 | */ |
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438 | def convertColumnToRowStructure(columnData) { |
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439 | |
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440 | // check if all columns have the dimensionality 2 |
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441 | if (columnData.every { it.value.every { it.value instanceof ArrayList } }) { |
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442 | |
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443 | def headers = [[],[]] |
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444 | |
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445 | columnData.each { category -> |
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446 | |
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447 | if (category.value.size()) { |
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448 | |
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449 | // put category keys into first row separated by null values |
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450 | // wherever there are > 1 columns per category |
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451 | headers[0] += [category.key] + [null] * (category.value.size() - 1) |
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452 | |
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453 | // put non-category column headers into 2nd row |
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454 | headers[1] += category.value.collect{it.key} |
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455 | |
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456 | } |
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457 | |
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458 | } |
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459 | |
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460 | def d = [] |
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461 | |
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462 | // add all column wise data into 'd' |
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463 | columnData.each { it.value.each { d << it.value } } |
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464 | |
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465 | // transpose d into row wise data and combine with header rows |
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466 | headers + d.transpose() |
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467 | } |
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468 | |
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469 | } |
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470 | |
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471 | /** |
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472 | * Export column wise data in Excel format to a stream. |
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473 | * |
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474 | * @param columnData Multidimensional map containing column data |
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475 | * @param outputStream Stream to write to |
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476 | * @param useOfficeOpenXML Flag to specify xlsx (standard) or xls output |
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477 | * @return |
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478 | */ |
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479 | def exportColumnWiseDataToExcelFile(columnData, outputStream, useOfficeOpenXML = true) { |
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480 | |
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481 | // transform data into row based structure for easy writing |
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482 | def rows = convertColumnToRowStructure(columnData) |
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483 | |
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484 | if (rows) { |
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485 | |
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486 | exportRowWiseDataToExcelFile(rows, outputStream, useOfficeOpenXML) |
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487 | |
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488 | } else { |
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489 | |
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490 | throw new Exception('Wrong column data format.') |
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491 | |
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492 | } |
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493 | |
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494 | } |
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495 | |
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496 | /** |
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497 | * Export row wise data in Excel format to a stream |
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498 | * |
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499 | * @param rowData List of lists containing for each row all cell values |
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500 | * @param outputStream Stream to write to |
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501 | * @param useOfficeOpenXML Flag to specify xlsx (standard) or xls output |
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502 | * @return |
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503 | */ |
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504 | def exportRowWiseDataToExcelFile(rowData, outputStream, useOfficeOpenXML = true) { |
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505 | Workbook wb = useOfficeOpenXML ? new XSSFWorkbook() : new HSSFWorkbook() |
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506 | Sheet sheet = wb.createSheet() |
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507 | |
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508 | exportRowWiseDataToExcelSheet( rowData, sheet ); |
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509 | |
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510 | wb.write(outputStream) |
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511 | outputStream.close() |
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512 | } |
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513 | |
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514 | /** |
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515 | * Export row wise data in CSV to a stream. All values are surrounded with |
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516 | * double quotes (" "). |
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517 | * |
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518 | * @param rowData List of lists containing for each row all cell values |
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519 | * @param outputStream Stream to write to |
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520 | * @return |
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521 | */ |
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522 | def exportRowWiseDataToCSVFile(rowData, outputStream) { |
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523 | |
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524 | outputStream << rowData.collect { row -> |
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525 | row.collect{ |
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526 | |
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527 | // omit quotes in case of numeric values |
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528 | if (it instanceof Number) return it |
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529 | |
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530 | def s = it.toString() |
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531 | |
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532 | def addQuotes = false |
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533 | |
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534 | // escape double quotes with double quotes if they exist and |
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535 | // enable surround with quotes |
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536 | if (s.contains('"')) { |
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537 | addQuotes = true |
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538 | s = s.replaceAll('"','""') |
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539 | } else { |
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540 | // enable surround with quotes in case of comma's |
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541 | if (s.contains(',') || s.contains('\n')) addQuotes = true |
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542 | } |
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543 | |
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544 | addQuotes ? "\"$s\"" : s |
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545 | |
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546 | }.join(',') |
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547 | }.join('\n') |
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548 | |
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549 | outputStream.close() |
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550 | } |
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551 | |
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552 | /** |
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553 | * Export row wise data for multiple assays in Excel format (separate sheets) to a stream |
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554 | * |
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555 | * @param rowData List of structures with rowwise data for each assay |
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556 | * @param outputStream Stream to write to |
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557 | * @param useOfficeOpenXML Flag to specify xlsx (standard) or xls output |
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558 | * @return |
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559 | */ |
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560 | def exportRowWiseDataForMultipleAssaysToExcelFile(assayData, outputStream, useOfficeOpenXML = true) { |
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561 | Workbook wb = useOfficeOpenXML ? new XSSFWorkbook() : new HSSFWorkbook() |
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562 | |
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563 | assayData.each { rowData -> |
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564 | Sheet sheet = wb.createSheet() |
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565 | |
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566 | exportRowWiseDataToExcelSheet( rowData, sheet ); |
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567 | } |
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568 | |
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569 | wb.write(outputStream) |
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570 | outputStream.close() |
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571 | } |
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572 | |
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573 | /** |
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574 | * Export row wise data in Excel format to a given sheet in an excel workbook |
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575 | * |
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576 | * @param rowData List of lists containing for each row all cell values |
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577 | * @param sheet Excel sheet to append the |
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578 | * @return |
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579 | */ |
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580 | def exportRowWiseDataToExcelSheet(rowData, Sheet sheet) { |
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581 | // create all rows |
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582 | rowData.size().times { sheet.createRow it } |
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583 | |
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584 | sheet.eachWithIndex { Row row, ri -> |
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585 | if( rowData[ ri ] ) { |
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586 | // create appropriate number of cells for this row |
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587 | rowData[ri].size().times { row.createCell it } |
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588 | |
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589 | row.eachWithIndex { Cell cell, ci -> |
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590 | |
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591 | // Numbers and values of type boolean, String, and Date can be |
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592 | // written as is, other types need converting to String |
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593 | def value = rowData[ri][ci] |
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594 | |
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595 | value = (value instanceof Number | value?.class in [boolean.class, String.class, Date.class]) ? value : value?.toString() |
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596 | |
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597 | // write the value (or an empty String if null) to the cell |
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598 | cell.setCellValue(value ?: '') |
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599 | |
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600 | } |
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601 | } |
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602 | } |
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603 | } |
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604 | |
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605 | } |
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