1 | import org.codehaus.groovy.grails.commons.GrailsApplication |
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2 | import grails.util.GrailsUtil |
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3 | import dbnp.studycapturing.* |
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4 | |
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5 | import dbnp.data.Ontology |
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6 | import dbnp.data.Term |
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7 | |
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8 | /** |
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9 | * Application Bootstrapper |
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10 | * @Author Jeroen Wesbeek |
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11 | * @Since 20091021 |
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12 | * |
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13 | * Revision information: |
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14 | * $Rev: 162 $ |
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15 | * $Author: duh $ |
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16 | * $Date: 2010-02-02 14:07:02 +0000 (di, 02 feb 2010) $ |
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17 | */ |
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18 | class BootStrap { |
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19 | def init = {servletContext -> |
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20 | // define timezone |
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21 | System.setProperty('user.timezone', 'CET') |
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22 | |
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23 | if (GrailsUtil.environment == GrailsApplication.ENV_DEVELOPMENT) { |
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24 | printf("development bootstrapping....\n\n"); |
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25 | |
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26 | // ontologies |
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27 | def speciesOntology = new Ontology( |
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28 | name: 'NCBI Taxonomy', |
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29 | shortName: 'Taxon', |
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30 | url: 'http://www.obofoundry.org/cgi-bin/detail.cgi?id=ncbi_taxonomy' |
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31 | ).with { if (!validate()) { errors.each { println it} } else save()} |
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32 | |
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33 | |
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34 | // terms |
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35 | def mouseTerm = new Term( |
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36 | name: 'Mus musculus', |
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37 | ontology: speciesOntology, |
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38 | accession: '10090' |
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39 | ).with { if (!validate()) { errors.each { println it} } else save()} |
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40 | def humanTerm = new Term( |
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41 | name: 'Homo sapiens', |
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42 | ontology: speciesOntology, |
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43 | accession: '9606' |
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44 | ).with { if (!validate()) { errors.each { println it} } else save()} |
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45 | |
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46 | def madmaxOntology = new Ontology( |
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47 | name: 'Madmax ontology', |
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48 | shortName: 'MDMX', |
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49 | url: 'madmax.bioinformatics.nl' |
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50 | ).with { if (!validate()) { errors.each { println it} } else save()} |
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51 | |
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52 | def treatmentTerm = new Term( |
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53 | name: 'ExperimentalProtocol', |
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54 | ontology: madmaxOntology, |
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55 | accession: 'P-MDMXGE-264' |
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56 | ).with { if (!validate()) { errors.each { println it} } else save()} |
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57 | |
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58 | |
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59 | def treatmentProtocol = new Protocol( |
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60 | name: 'MADMAX Experimental Protocol', |
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61 | reference: treatmentTerm |
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62 | ).with { if (!validate()) { errors.each { println it} } else save()} |
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63 | |
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64 | |
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65 | // added by Jahn for testing the event views |
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66 | def treatmentProtocol2 = new Protocol( |
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67 | name: 'MADMAX Experimental Protocol 2', |
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68 | reference: treatmentTerm |
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69 | ).with { if (!validate()) { errors.each { println it} } else save()} |
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70 | |
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71 | |
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72 | |
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73 | treatmentProtocol |
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74 | .addToParameters(new ProtocolParameter( |
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75 | name: 'Diet', |
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76 | type: ProtocolParameterType.STRINGLIST, |
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77 | listEntries: ['10% fat (palm oil)','45% fat (palm oil)'])) |
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78 | .addToParameters(new ProtocolParameter( |
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79 | name: 'Compound', |
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80 | type: ProtocolParameterType.STRINGLIST, |
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81 | listEntries: ['Vehicle','Leptin'])) |
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82 | .addToParameters(new ProtocolParameter( |
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83 | name: 'Administration', |
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84 | type: ProtocolParameterType.STRING)) |
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85 | .save() |
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86 | |
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87 | |
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88 | // added by Jahn for testing the event views |
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89 | treatmentProtocol2 |
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90 | .addToParameters(new ProtocolParameter( |
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91 | name: 'Diet', |
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92 | type: ProtocolParameterType.STRINGLIST, |
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93 | listEntries: ['99% fat (crude oil)','1% fat (palm oil)'])) |
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94 | .addToParameters(new ProtocolParameter( |
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95 | name: 'Compound', |
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96 | type: ProtocolParameterType.STRINGLIST, |
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97 | listEntries: ['Vehicle','Leptin'])) |
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98 | .addToParameters(new ProtocolParameter( |
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99 | name: 'Administration', |
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100 | type: ProtocolParameterType.STRING)) |
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101 | .save() |
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102 | |
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103 | |
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104 | |
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105 | // create system user |
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106 | /* |
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107 | def systemUser = userService.createUser(InstanceGenerator.user( |
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108 | username: 'system', |
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109 | pass: 'system', |
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110 | passConfirm: 'system', |
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111 | enabled: true |
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112 | )) |
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113 | */ |
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114 | |
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115 | // Mouse template |
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116 | def mouseTemplate = new Template( |
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117 | name: 'Mouse' |
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118 | ).addToSubjectFields(new TemplateSubjectField( |
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119 | name: 'Genotype',type: TemplateFieldType.STRINGLIST)) |
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120 | .addToSubjectFields(new TemplateSubjectField( |
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121 | name: 'Gender',type: TemplateFieldType.STRINGLIST, listEntries: ['Male','Female'])) |
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122 | .addToSubjectFields(new TemplateSubjectField( |
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123 | name: 'Age',type: TemplateFieldType.INTEGER)) |
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124 | .addToSubjectFields(new TemplateSubjectField( |
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125 | name: 'Cage',type: TemplateFieldType.INTEGER)) |
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126 | .with { if (!validate()) { errors.each { println it} } else save()} |
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127 | |
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128 | |
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129 | //events |
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130 | def eventTreatment = new EventDescription( |
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131 | name: 'Treatment', |
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132 | description: 'Experimental Treatment Protocol NuGO PPS3 leptin module', |
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133 | classification: treatmentTerm, |
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134 | protocol: treatmentProtocol |
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135 | ).with { if (!validate()) { errors.each { println it} } else save()} |
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136 | |
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137 | |
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138 | // studies |
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139 | def exampleStudy = new Study( |
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140 | title:"NuGO PPS3 mouse study leptin module", |
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141 | code:"PPS3_leptin_module", |
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142 | researchQuestion:"Leptin etc.", |
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143 | description:"C57Bl/6 mice were fed a high fat (45 en%) or low fat (10 en%) diet after a four week run-in on low fat diet. After 1 week 10 mice that received a low fat diet were given an IP leptin challenge and 10 mice of the low-fat group received placebo injections. The same procedure was performed with mice that were fed the high-fat diet. After 4 weeks the procedure was repeated. In total 80 mice were culled.", |
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144 | ecCode:"2007117.c", |
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145 | startDate: Date.parse('yyyy-MM-dd','2007-12-11'), |
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146 | template: mouseTemplate |
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147 | ).with { if (!validate()) { errors.each { println it} } else save()} |
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148 | |
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149 | def x=1 |
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150 | 12.times { |
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151 | def currentSubject = new Subject( |
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152 | name: "A" + x++, |
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153 | species: mouseTerm, |
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154 | template: mouseTemplate, |
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155 | templateStringFields: ["Genotype" : "C57/Bl6j", "Gender" : "Male"], |
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156 | templateIntegerFields: ["Age" : 17, "Cage" : (int)(x/2)] |
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157 | ).with { if (!validate()) { errors.each { println it} } else save()} |
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158 | |
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159 | exampleStudy.addToSubjects(currentSubject) |
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160 | .addToEvents(new Event( |
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161 | subject: currentSubject, |
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162 | startTime: Date.parse('yyyy-MM-dd','2008-01-07'), |
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163 | endTime: Date.parse('yyyy-MM-dd','2008-01-14'), |
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164 | eventDescription: eventTreatment, |
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165 | parameterStringValues: ['Diet':'10% fat (palm oil)','Compound':'Vehicle','Administration':'intraperitoneal injection']) |
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166 | ).with { if (!validate()) { errors.each { println it} } else save()} |
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167 | } |
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168 | |
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169 | |
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170 | def secondStudy = new Study( |
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171 | title:"NuGO PPS1 mouse study leptin module", |
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172 | code:"PPS1", |
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173 | researchQuestion:"etc.", |
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174 | description:"C57Bl/6 mice were fed a high fat (45 en%) or low fat (10 en%) diet after a four week run-in on low fat diet. After 1 week 10 mice that received a low fat diet were given an IP leptin challenge and 10 mice of the low-fat group received placebo injections. The same procedure was performed with mice that were fed the high-fat diet. After 4 weeks the procedure was repeated. In total 80 mice were culled.", |
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175 | ecCode:"2007.c", |
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176 | startDate: Date.parse('yyyy-MM-dd','2007-12-11'), |
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177 | template: mouseTemplate |
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178 | ).with { if (!validate()) { errors.each { println it} } else save()} |
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179 | |
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180 | def y=1 |
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181 | 5.times { |
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182 | def currentSubject = new Subject( |
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183 | name: "A" + y++, |
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184 | species: mouseTerm, |
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185 | template: mouseTemplate, |
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186 | templateStringFields: ["Genotype" : "C57/Bl6j", "Gender" : "Male"], |
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187 | templateIntegerFields: ["Age" : 17, "Cage" : (int)(y/2)] |
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188 | ).with { if (!validate()) { errors.each { println it} } else save()} |
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189 | |
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190 | secondStudy.addToSubjects(currentSubject) |
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191 | .addToEvents(new SamplingEvent( |
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192 | subject: currentSubject, |
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193 | startTime: Date.parse('yyyy-MM-dd','2008-01-07'), |
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194 | endTime: Date.parse('yyyy-MM-dd','2008-01-14'), |
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195 | eventDescription: eventTreatment, |
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196 | parameterStringValues: ['Diet':'10% fat (palm oil)','Compound':'Vehicle','Administration':'intraperitoneal injection']) |
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197 | ).with { if (!validate()) { errors.each { println it} } else save()} |
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198 | } |
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199 | |
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200 | // new Study(title:"example",code:"Excode",researchQuestion:"ExRquestion",description:"Exdescription",ecCode:"ExecCode",dateCreated:new Date(),lastUpdated:new Date(),startDate:new Date()).save() |
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201 | // new Study(title:"testAgain",code:"testcode",researchQuestion:"testRquestion",description:"testdescription",ecCode:"testCode",dateCreated:new Date(),lastUpdated:new Date(),startDate:new Date()).save() |
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202 | // new Study(title:"Exampletest",code:"Examplecode",researchQuestion:"ExampleRquestion",description:"Exampledescription",ecCode:"ExampleecCode",dateCreated:new Date(),lastUpdated:new Date(),startDate:new Date()).save() |
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203 | } |
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204 | } |
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205 | |
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206 | def destroy = { |
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207 | } |
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208 | } |
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